CD43 antibody (PE)

Catalog No. ABIN610087

This Mouse Monoclonal antibody specifically detects CD43 in FACS, WB, IHC and Func. It exhibits reactivity toward Human and has been mentioned in 2+ publications.

Quick Overview for CD43 antibody (PE) (ABIN610087)

Target: CD43 (SPN) (Sialophorin (SPN))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD43 antibody is conjugated to PE

Application: Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (IHC), Functional Studies (Func)

Clone: DFT-1

Product Details anti-CD43 Antibody (PE)

Specificity: Epitope A of the CD43 Molecule on pMN of about 135 kd.

Purification: Gel filtration

Immunogen: Human KG-1 tumor cells.

Isotype: IgG1

Application Details

Application Notes: Approved: Flo, Func, IHC, WB

Usage: Function: Partially induces apoptosis in hemopoietic progenitor cells and also induces hemopoietic aggregation. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 50 mM sodium phosphate,  pH 7.5, 500 mM potassium chloride, 150 mM sodium chloride, 15 % Glycerol, 0.2 % BSA, 0.04 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do not freeze. Product is photosensitive and should be protected from light.

Storage: 4 °C

Storage Comment: Store at 4°C. Do not freeze. Protect from light.

References for anti-CD43 antibody (PE) (ABIN610087)

Kim, Feldman: "Insulin-like growth factor I prevents mannitol-induced degradation of focal adhesion kinase and Akt." in: The Journal of biological chemistry, Vol. 277, Issue 30, pp. 27393-400, (2002) (PubMed).

Clancy, Rediske, Tang, Nijher, Frenkel, Philips, Abramson: "Outside-in signaling in the chondrocyte. Nitric oxide disrupts fibronectin-induced assembly of a subplasmalemmal actin/rho A/focal adhesion kinase signaling complex." in: The Journal of clinical investigation, Vol. 100, Issue 7, pp. 1789-96, (1997) (PubMed).

Target Details for CD43

Target: CD43 (SPN) (Sialophorin (SPN))

Alternative Name: CD43

Background: Name/Gene ID: SPN

Synonyms: SPN, GPL115, Leukosialin, Leukocyte sialoglycoprotein, Galactoglycoprotein, GALGP, Sialophorin, LSN, CD43, CD43 antigen

Gene ID: 6693

UniProt: P16150

Pathways: Regulation of Leukocyte Mediated Immunity